"The superior vena cava can become obstructed and involvement of the heart and pericardium can occur. Lymphatic obstruction and spread can lead to dyspnea, hypoxia, and pleural effusions. Distant metastatic disease can affect most organs. Neurologic symptoms may suggest brain metastases or spinal cord compression, and pain could indicate bone metastases" (Mazzone 2004). Treatment

Surgery is the usual recourse for early-stage non-small cell lung cancer Radiotherapy has been used with curative intent in early-stage non-small cell lung cancer, either in patients who cannot tolerate surgery or in those who elect not to undergo surgery. Chemoradiotherapy to shrink the tumor followed by surgery, or surgery followed by radiotherapy or chemoradiotherapy may be used in more aggressive cases (Mazzone...

"Radiotherapy can be used to palliate bone pain related to metastatic disease, hemoptysis, or symptoms of airway obstruction. Invasive bronchoscopic procedures (laser ablation, electrocautery, stent placement, and so forth) may palliate patients with airway obstruction" (Mazzone, 2004).
Works Cited

Huether, Sue & Kathryn McCance. (2008). Understanding Pathophysiology. 4th ed. Mosby.

Mazzone, Peter. (2004, 6 May). Lung cancer. Cleveland clinic. Retrieved 2 Nov 2008 at http://www.clevelandclinicmeded.com/medicalpubs/diseasemanagement/pulmonary/lungcancer/lungcancer.htm#signsymptoms

Lung cancer